![]() ![]() Infant and Small Children Dose Estimates of DIGOXIN IMMUNE FAB (in mg)įrom Steady-State Serum Digoxin Concentration Serum levels done prior to 6 hours can still be used to calculate dose but may overestimate the dose required. Serum concentration (nmol/L) x 0.781 x patient weight (kg)ĭigoxin levels done greater than 6 hours post dose more accurately reflect toxicity. *Note: Round up to the next highest number of vials. Repeat if needed for ongoing toxicity.Īmount Ingested Unknown: Dose (in vials)* = With hemodynamic compromise: Give 2-4 vials over 30 minutes by IV infusion.If full amount not available, give closest amount available. Cardiac arrest imminent or present: 10 vials by direct IV, repeat 5 - 10 vials as needed for ongoing toxicity, after 3 - 5 min. ![]() ![]() Acute or chronic life-threatening digoxin toxicity (or other cardioactive steroid: digitoxin, plants, toad venom) : tachy or brady arrhythmias, hypotension, hyperkalemia (greater than 5 mEq/L) and/or a digoxin serum level of greater than 12.8 nmol/L (greater than 10 ng/mL).Įmpiric Dosing (Unknown level and severe toxicity).ALERT: This item is found in the refrigerator antidote kit. ![]()
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